Waterpipe tobacco products: nicotine labelling versus nicotine delivery

Tobacco & Nicotine - nicotine as therapy

A nicotine delivery device without the nicotine? Tobacco industry development of low nicotine cigarettes.

BACKGROUND Defining harm reduction and regulating potentially reduced exposure products (PREPs), including low nicotine products, are key issues in tobacco control policy. The US Congress has been considering legislation authorising the Food and Drug Administration (FDA) to regulate tobacco products. OBJECTIVE To investigate tobacco industry perceptions, interests, motivations, and knowledge ...

Global surveillance of oral tobacco products: total nicotine, unionised nicotine and tobacco-specific N-nitrosamines.

OBJECTIVE Oral tobacco products contain nicotine and carcinogenic tobacco-specific N-nitrosamines (TSNAs) that can be absorbed through the oral mucosa. The aim of this study was to determine typical pH ranges and concentrations of total nicotine, unionised nicotine (the most readily absorbed form) and five TSNAs in selected oral tobacco products distributed globally. METHODS A total of 53 ora...

smokeless tobacco, switching to products with greater nicotine delivery may also contribute to nicotine dose escalation (US DHHS

Animal studies have proved useful in establishing the actual development of tolerance to nicotine, the magnitude of such tolerance, and mechanisms that underlie this tolerance. The majority of these studies have used the rat and mouse as experimental subjects. Most of the chronic tolerance studies using the rat have focused on the effects of nicotine on locomotor activity. Depression of locomot...

Waterpipe tobacco smoking: what is the evidence that it supports nicotine/tobacco dependence?

OBJECTIVE Waterpipe tobacco smoking (WTS) involves passing tobacco smoke through water prior to inhalation, and has spread worldwide. This spread becomes a public health concern if it is associated with tobacco-caused disease and if WTS supports tobacco/nicotine dependence. A growing literature demonstrates that WTS is associated with disability, disease and death. This narrative review examine...